Best Kerning Practices

Hello,
I’ve read the tutorial on kerning, but I am trying to understand what the best (or most typical) practices are for kerning.

At first I tried Method A:
Setting all left and right kerning for each character as zero, then adding group and individual kerning pairs.
However, it became difficult to manage all the kerning pairs (I had maybe about 200), and for some reason the kerning pairs would not appear when using it as a web font.

Next, I tried Method B:
Adding “base” kerning for each character (still using groups for characters with similar shapes), then adding in specific kerning pairs as needed. This reduced the total number of kerning pairs I needed significantly, and the kerning pairs showed up without problem in web.

Is there a different practice in kerning that I should try or is this how others typically kern?
Also, setting the kerning for example as 40 in illustrator is a different spacing than the 40 I set in Glyphs. Am I correct in understanding that this us because Glyphs uses “units” different than Illustrator?

Thanks.

this sounds like you confuse spacing with kerning. Spacing | Glyphs

Only after all the sidebearings are as good as possible, start with kerning. And only add kerning to irregular pairs like To and f).

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