If I select two consecutive nodes, say the bottom of a rectangle, by clicking one then shift-clicking the next, then Ctrl-click for a context menu, included on it are Add Cap, Reconnect Nodes, Open Corner, Add Corner, and others.
If I instead select those nodes by drag-clicking over them, those four menu options don’t appear.
(I understand that some of these options wouldn’t make sense for some of the things you might select that way, but for selections that are appropriate I think Glyphs should offer them.)