When using “Set Anchors”, “Reset Anchors”, or similar automatic functions to add anchors, some anchors are not added automatically. GlyphsData.xml is incomplete for Latin, Greek and Cyrillic as many orthographies use combining marks with letters that are currently not covered.
It seems there are either obvious inconsistencies and general omissions.
One obvious inconsistency is for example “vturned” having anchors=“top, bottom” but “Vturned” having no anchors defined.
So using “Set Anchors” will add top and bottom anchors to vturned but non to Vturned. Yet both are used in systems that use combining marks, for example Northern Emberá, Wounmeu or Eastern Dan use the letter in lowercase and uppercase with top marks. Other systems also use the letter with bottom marks, for example Oneida.
Generally, if a font has a combining mark with an anchor, all the base letters, or at least all base letters that already have some anchors and their case variant, should have an anchor for it.
For example, there’s no reason for “a” to have anchors=“top, bottom, ogonek” but for “eopen” or “vturned” to only have anchors=“top, bottom”, especially considering ɛ̨ or ʌ̨ are or have been used.